MICROWAVE CHEMICAL SYNTHESIS
In 1986, the first peer-reviewed literature appeared on the ability of Microwave energy to accelerate organic chemical transformation. Since then, several thousand articles have been produced dealing with the subject of Microwave-Assisted organic synthesis.
To understand the effects of Microwave energy on a chemical reaction, we must start with the solvent and the reactants.
In order to complete the reaction, heat is introduced to provide the activation energy necessary to produce the required transition state. Once there, the reaction occurs and the end product is realized.
In the past, some form of conventional/conductive heat was required to bring the bulk to temperature. Once there, results were dependent on random molecular orientation. The process could take hours or even days.
The introduction of Microwave energy has reduced many of these reactions to minutes, while at the same time improving yield.
If this is a simple thermal phenomenon, how can this be? Are the experimental protocols and recipe temperatures not the same as with other heat forms? Does it take days to bring solvents to temperature through conduction?
Clearly, whatever the explanation of the full dynamic, Microwave is producing effects on the molecular level that other heat forms cannot.
Although Microwave has found significant use for the chemistry of pharmaceuticals, it is still relatively new for industrial applications. Thermex Thermatron, LP is currently engaged in the pursuit of industrial enhancements through the development of application techniques, novel applicator designs and the use of Programmable Logic Control (PLC) and customized software.
Feel free to review select hardware developed for use in a variety of applications. For assistance in selecting the appropriate system for your needs, please contact one of our Application Engineers.
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